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Comparison of the main steps and features of conventional molecular mutation detection methods
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Comparison of the main steps and features of conventional molecular mutation detection methods
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Comparison of the main steps and features of conventional molecular mutation detection methods
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Comparison of the main steps and features of conventional molecular mutation detection methods
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Comparison of the main steps and features of conventional molecular mutation detection methods
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Comparison of the main steps and features of conventional molecular mutation detection methods

Journal: Theranostics

Article Title: Surface Enhanced Raman Spectroscopy (SERS) for the Multiplex Detection of Braf, Kras, and Pik3ca Mutations in Plasma of Colorectal Cancer Patients

doi: 10.7150/thno.22502

Figure Lengend Snippet: Comparison of the main steps and features of conventional molecular mutation detection methods

Article Snippet: Denaturing gradient gel electrophoresis (DGGE) , + , - , optional PCR , different melting behavior , fluorescence, electrophoresis , high sensitivity, detects ~80-90% of point mutations , low throughput, complex primer design.

Techniques: Comparison, Mutagenesis, Amplification, Multiplex Assay, Electrophoresis, Real-time Polymerase Chain Reaction, Fluorescence, Ligation, Sequencing, Mass Spectrometry, Denaturing Gradient Gel Electrophoresis